We are now about four months away from Buffalo Bills football. It’s time for the Bills prove they belong among the best in the league. I’m going to break down each upcoming regular season matchup and predict the Bills’ 2022 season record. The Bills have the 12th easiest schedule in the league and have a chance to post an impressive record.

The Bills have five primetime games this season, starting off with a bang by going to LA for the NFL’s season opener to face off against the reigning Super Bowl Champion Los Angeles Rams on Thursday Night Football.  

Week 1: Buffalo Bills at Los Angeles Rams  

Every football fan should mark their calendars for this game as Von Miller faces off against his former team. Both teams are very real Super Bowl contenders this season as the Rams have a chance to run it back.  

The Rams have lost a few key pieces to their Super Bowl winning roster, including Von Miller (signed to Bills) and Andrew Whitworth (retired.) There are also some questions about where Odell Beckham Jr. may end up this offseason after unfortunately tearing his ACL in the Super Bowl.  

The Rams still have an amazing team despite these few loses. And unfortunately, the Rams will beat the Bills start off the season with a loss with the nation watching. Prediction (0-1).

Week 2: Buffalo Bills vs Tennessee Titans  

The Bills are going to be facing off against the Titans in week two on Monday Night after losing in week one. The Bills lost this matchup last time they faced off and Derrick Henry ran all over the Bills defense. The Bills have picked up many weapons on the d-line in order to stop the run and will be more prepared for the Titans.  

The Titans lost their star wide receiver AJ Brown this offseason and replaced him with Treylon Burks (rookie wide receiver from Arkansas). The Titans defense won’t be ready for the Bills offense this time. The Bills lost last time the two teams played, 34-31, but the Bills will be looking for revenge this time. Chalk this one up as a win. Prediction (1-1).

Week 3: Buffalo Bills at Miami Dolphins 

The Dolphins made a crazy trade this offseason, trading with the Chiefs for Tyreek Hill. The Dolphins are a solid team and are not a team that Buffalo will walk all over any more. But, the addition of Tyreek Hill will not be enough to beat the Bills’ defense. The Bills will be ready for trick plays with Hill and short drag routes, forcing Tua Tagovailoa to throw the football.

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The Dolphins are not ready to overcome Josh Allen and the Bills quite yet, as the Bills will pickup their second win on the season. Prediction (2-1).

Week 4: Buffalo Bills at Baltimore Ravens  

The Bills are set to face off against the Ravens in Week 4 and it should be a fun one. The last time the Bills played the Ravens was the AFC Divisional Round of the playoffs in 2020 where the Bills beat the Ravens 17-3.

The Ravens are not a team to be pushed around and they’re one of the AFC’s underdogs this year. They’ll have one of the best quarterbacks in the league in Lamar Jackson, and he will be healthy. But, I believe the Bills will have just enough to beat the Ravens in this week and will rack up their third straight win. Prediction (3-1).

Week 5: Buffalo Bills vs Pittsburgh Steelers 

The Steelers went into the NFL Draft thinking “quarterback” and left feeling satisfied as they have gotten their quarterback for the foreseeable future. The Steelers have one of the best defenses in the league right now, in large part due to TJ Watt. They also added former Jaguars linebacker Myles Jack.  

The Steelers have made many moves this offseason to put them in a good situation but the Bills have the ability to stop the Steelers offense, no matter who is at quarterback for them. The Bills will play the Steelers at home, where they lost in the opener last year, and win it in front of Bills Mafia this time around to string together four consecutive wins. Prediction (4-1).

Week 6: Buffalo Bills at Kansas City Chiefs  

Well, well, well… the Chiefs, again. The Chiefs have been marked on the Bills’ calendars since the Divisional Round of the playoffs last season. The Chiefs have lost their star wide receiver Tyreek Hill to the Miami Dolphins and now have Juju Smith-Schuster as their number one receiver. They’ll still have one of the best quarterbacks in the league along with one of the best tight ends in the league, and a likely-improved defense.  

This is going to be a tough game for the Bills to win. The Bills will go into Kansas City and lose to the Chiefs again. But, they’ll most likely meet in the postseason, and hopefully it will be in Western New York that time around. Prediction (4-2).

Week 7: Bye Week  

Week 8: Buffalo Bills vs Green Bay Packers  

The Bills will be facing off against the Packers at home in Week 8 on Sunday Night Football. The Packers are a very good team with a very good quarterback, and they’ll remain a really good team even with the loss of their star wide receiver Davante Adams to the Raiders. However, they don’t have enough weapons this year on offense to succeed like last season.

The Bills are a team that will have the offensive firepower at home to be able to beat the talented Packers. The Bills will win in Week 8 at home. Prediction (5-2).

Week 9: Buffalo Bills at New York Jets  

The Jets have made many moves this offseason and on paper look like a very good team. They have had arguably the best draft by any team, selecting cornerback Ahmad Gardner with the fourth overall pick and wide receiver Garrett Wilson with the tenth pick.  

The Jets still have some work to do before they can compete with the Bills but they have done a great job this offseason in free agency and in the draft. The Bills will take the win in Week 9 against the Jets. Prediction (6-2).

Week 10: Buffalo Bills vs Minnesota Vikings  

The Bills will be taking on the Vikings in Week 10. The Vikings have a very talented offense with one of the best young receivers in Justin Jefferson and one of the best running backs in the league in Dalvin Cook.  

The Vikings won’t be able to overpower the Bills defense in Buffalo though, as the Bills will pick up their seventh win on the season. Prediction (7-2).

Week 11: Buffalo Bills vs Cleveland Browns 

The Bills will be facing the Browns at home in Week l1. The Browns have just acquired Deshaun Watson after him not playing last season for the Texans due to sexual assault charges, and the length of the suspension is up in the air for this year. The last time the Bills played Deshaun Watson was in the 2019 Wild Card Round against the Texans where the Bills lost 22-19.   

The Browns will be very different with the addition of WR Amari Cooper, and despite the additions, the Bills should be able to win this game no matter who is playing QB for Cleveland. Prediction (8-2).

Week 12: Buffalo Bills at Detroit Lions  

The Bills will take on the Lions in Week 12 on Thanksgiving day. The Bills played on Thanksgiving night last season against the Saints and came away victorious. The Lions had the second pick in this year’s NFL Draft and have selected pass rusher Aidan Hutchinson from Michigan.  

The Lions are a developing young team with a lot of young talent but aren’t very good right now. The Lions will not be able to contain the Bills explosive offense. Josh Allen is 2-0 on Thanksgiving, and they’ll make it 3-0 as America watches on while diving into their Thanksgiving plates. Prediction (9-2).

Week 13: Buffalo Bills at New England Patriots  

The Bills will be facing the Patriots on Thursday Night Football in Week 13. The last time these two faced each other was the Wild Card Round last year, as the Bills demolished the Patriots, scoring a touchdown on every single one of their seven drives and breaking playoff records.

The Patriots have not done much compared to other AFC East teams this offseason and it will show when the season starts. The Bills will beat the Patriots on Thursday night, advancing to ten wins. Prediction (10-2).

Week 14: Buffalo Bills vs New York Jets  

The Bills will be facing the Jets for the second time this season. We’ve already went over some of the key moves the Jets have made this offseason but the Bills are still a better all-around football team with more experience together, and the Jets record at this point might not be great. The Bills will win their second meeting with the Jets and rack up their eleventh win. Prediction (11-2)

Week 15: Buffalo Bills vs Miami Dolphins  

In the second matchup of the year against Miami, the Bills will be at home where they have manhandled the Dolphins in recent years. The Dolphins don’t have a good enough quarterback to beat the Bills defense, but they do have quality running backs and they can keep it close for a bit. But, the Bills will win this matchup once again. Prediction (12-2).

Week 16: Buffalo Bills at Chicago Bears  

The Bills will be facing off against Justin Fields and the Chicago Bears in Week 16. The Bills should have an advantage as they face a young quarterback in Justin Fields. The Bears have added a few wide receivers that should help the rookie, including Byron Pringle and Velus Jones Jr. But, as we’ve seen, Sean McDermott loves facing off against young QBs.

The Bears defense on the other hand aren’t going to match well with the Bills offense. They have some good names on that side of the ball but the Bills should be able to win in that aspect. The Bills are going to win this game. Prediction (13-2).

Week 17: Buffalo Bills at Cincinatti Bengals  

The Bills are facing the Bengals in Week 17. The Bengals played against the LA Rams in last season’s Super Bowl and lost. They’re a very good, young team and had a great chance at winning the Super Bowl if it wasn’t for their horrible o-line. The Bengals have tried to fix that this off-season by adding right tackle La’el Collins, right guard Alex Cappa, and center Ted Karras.

Despite the additions for Cincy, the Bills are better on both sides of the ball and more experienced. Josh Allen will shine brightest in primetime, especially if there’s seeding at stake. The Bills will win this game in Week 17 and advance to 14-2. Prediction (14-2).

Week 18: Buffalo Bills vs New England Patriots  

The final game of the season for Buffalo will be their second matchup against the Patriots. We have already gone over what the Patriots have done this offseason, and it wasn’t very much at all. They had an underwhelming draft and don’t look ready to take on the Bills on both sides of the ball.  

The Bills are going to win this game in the final week of the regular season and possibly earn the number one seed in the AFC with a record of 15-2.

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